Insulin degludec
CAS No. 844439-96-9
Insulin degludec ( —— )
产品货号. M25046 CAS No. 844439-96-9
Insulin degludec is an ultra-long-acting form of insulin used for the treatment of hyperglycemia caused by type 1 and type 2 dabetes. Insulin degludec shows binding efficiency with an IC50 value of 19.59 nM/L for insulin receptor. Insulin degludec can be used for the research of type 1 and type 2 diabetes.
纯度: >98% (HPLC)
规格 | 价格/人民币 | 库存 | 数量 |
5MG | ¥2682 | 有现货 |
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10MG | ¥4464 | 有现货 |
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100MG | 获取报价 | 有现货 |
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200MG | 获取报价 | 有现货 |
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500MG | 获取报价 | 有现货 |
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1G | 获取报价 | 有现货 |
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生物学信息
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产品名称Insulin degludec
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述Insulin degludec is an ultra-long-acting form of insulin used for the treatment of hyperglycemia caused by type 1 and type 2 dabetes. Insulin degludec shows binding efficiency with an IC50 value of 19.59 nM/L for insulin receptor. Insulin degludec can be used for the research of type 1 and type 2 diabetes.
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产品描述Insulin degludec is an ultra-long-acting form of insulin used for the treatment of hyperglycemia caused by type 1 and type 2 dabetes. Insulin degludec shows binding efficiency with an IC50 value of 19.59 nM/L for insulin receptor. Insulin degludec can be used for the research of type 1 and type 2 diabetes.Insulin degludec (0.001-1000 nM; 12 h) binds with insulin receptor with an IC50 value of 19.59 nM/L.Insulin degludec (200 nM; 10 min) increases glucose uptake in HL-1 cells.
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同义词——
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通路Tyrosine Kinase
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靶点Insulin Receptor
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受体——
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研究领域——
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适应症——
化学信息
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CAS Number844439-96-9
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分子量——
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分子式——
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纯度>98% (HPLC)
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溶解度0.1 M HCL : 50 mg/mL (ultrasonic and adjust pH to 2 with 0.1 M HCL)
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SMILESN/A
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
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[D-Ala2]-GIP (human)
Highly potent GIP receptor agonist (EC50 = 630 ± 119 pM). Displays equivalent cAMP stimulating properties and improved resistance to enzymatic degradation compared to native GIP in cells expressing wild type GIP receptor. Improves glucose tolerance, insulin release and cognitive function in various animal models of obesity and diabetes. Displays neuroprotective effects in an MPTP model of PD.
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S961
S961 is an high-affinity and selective insulin receptor (IR) antagonist with IC50s of 0.048, 0.027, and 630 nM for HIR-A, HIR-B, and human insulin-like growth factor I receptor (HIGF-IR) in SPA-assay, respectively.
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MSDC-0160
A new generation insulin sensitizer and mitochondrial target of thiazolidinediones (mTOT) modulator that has low affinity for binding and activation of PPARγ (EC50=23.7 uM).